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Faculty Research Highlights

The IGPBS faculty are associated with the Departments of Biochemistry, Microbiology & Immunology, Pathology and Anatomical Sciences, Pharmacology and Toxicology, Physiology and Biophysics, and Structural Biology, as well as the Neuroscience program at the University of Buffalo. These faculty members, which includes over 100 individuals, have diverse research interests encompassing virtually all aspects of modern biological and biomedical science. Areas of research focus include:

  • Molecular & cellular biology
  • Microbial pathogenesis Neurobiology Signal transduction
  • Regulation of gene expression
  • Genomics & proteomics
  • Toxicology
  • Cardiopulmonary physiology & pathophysiology
  • Protein folding and structure
  • Drug abuse
  • Immunology & immunopathology
  • Endocrinology Regulation of transcription & translation
  • Cell growth, development & differentiation
  • Virology Ion channel kinetics & structure
  • Molecular basis of disease & neurodegenerative disorders
  • Parasitology
  • Molecular genetics
  • Behavioral pharmacology
  • Aging Ion transport
  • Proteins & metalloenzymes
  • Apoptosis & cell death Regulation of metabolism
  • Gene therapy
  • Cytoskeleton & cell motility

Many of the faculty have combined to form multidisciplinary research focus groups such as:

  • Center for Advanced Eye Research
  • Center for Cardio-Pulmonary Biology
  • Center for Metaolic Regulation
  • Center for Molecular Kinetics and Ion Channel Biology
  • Center for Molecular Mechanisms of Disease and Aging
  • Center for Perinatology and Developmental Biology
  • Markey Center for Microbial pathogenesis
  • Toshiba Center for Stroke Research
  • Toxicology Research Center
  • University Structural Biology Initiative

Highlights of some Research Accomplishments by faculty members at Buffalo:

  • Production of the bacterial artificial chromosome (BAC) libraries for the National Human
  • Genome project
  • Development of the test for phenylketonaria in newborns
  • Development of PSA test
  • Screening test for sickle cell disease
  • Transgenic potato-edible vaccine for Hepatitis C
  • Vaccine for the prevention of Haemophilus influenza infections
  • Development of fetal viability test
  • Patented high throughput, robotic crystallization method
  • Pioneered interferon treatment for Multiple Sclerosis
  • Development of artificial blood
  • Development of Liquivent for liquid ventilation
  • Development of Nicorette gum
  • Surfactant therapy for respiratory distress syndrome in premature newborns