Faculty of the Department of Psychiatry at the University at Buffalo have extensive research experience in a variety of NIH and industry sponsored projects including clinical trials, outcome studies,  and studies of drug metabolism.  In collaboration with colleagues throughout the university, psychiatry faculty have conducted studies of brain imaging, health services interventions, epidemiological risk factor research,  experimental investigations, and longitudinal cohort studies.  Faculty in the department have also conducted Phase II, Phase III, and Phase IV FDA studies.  The department maintains extensive collaborative with other departments at the University at Buffalo, including Nuclear Medicine, Neurology, Psychology, Family Medicine,  Rehabilitative Medicine, and the Communicative Disorders.  In addition,  faculty collaborate with researcher at the Roswell Park Cancer Institute and the Research Institute on Addictions. 

         The department has substantial resources to support its research program.  The department maintains a Clinical Research Center, which is staffed by a full time Research Director and a full time Research Coordinator, and additional administrative support is provided to the CRC.   Current research utilizing these facilities include a double-blind study of pharmaceutical interventions for patients with Bipolar I disorder,  efficacy and pharmacokinetics of antipsychotic medications in elderly patients, safety and efficacy for medications for acute mania,  safety and tolerability of treatments for Dementia of the Alzheimer's Type, and studies of pharmacological interventions with adolescents with schizophrenia and Bipolar disorder.  In addition, faculty are pursuing research interests in biopsychosocial factors in chronic disease,  hormonal modulation of brain and behavior, hormone related changes in mood and behavior in women interventions for children with ADHD,  developmental studies of offspring of substance abusers,  psychosocial studies of the development of alcohol problems among married couples, and the integration of bioinformatics and clinical information.

          The clinical services of the department and our collaborations with other clinical facilities support the many research efforts of the department.  Department faculty provide clinical services in both inpatient and outpatients settings in affiliated institutions, including the Erie County Medical Center, and the Kaleida Health System, including the Children's Hospital of Buffalo.   Faculty also provide services at the Veterans WNY Healthcare System, the Buffalo Psychiatric Center, and the Children's Psychiatric Center.  We maintain excellent relationships with psychiatrists in the community and have established a practice network to further clinical and research missions of the department.