5R01MH064154-03
    Depression and Child Asthma: Effects of Family Relations
    Beatrice L. Wood, Ph.D. (PI) 716 878-7645 bwood@buffalo.edu
    Bruce D. Miller, M.D., Co-PI
    2002-2007 NIMH
    Direct costs $2,339,106.

Parenting and Infant Development in Alcoholic Familes
PI  Rina Eiden (Research Institute on Addictions)
Co-I Kenneth Leonard
         Craig Colder (Psychology)
         Kerry Grohman (RIA)
         Ellen Edwards (RIA)
Sponsor NIAAA
Current Funding   $3,342,981
Time Curently in 13th year
This longitudinal study examines the role of parents' alcohol problems on developmental trajectories of children's self-regulation, peer relationships, and cognitive development using a transactional approach that considers multiple influences on parenting and child development. These include factors associated with parents' alcohol problems such as depression and antisocial behavior as well as contextual factors such as marital aggression, life stress, and support .   Families were assessed when children were 12, 18, 24, 36 months of age, at 4 years,  upon entry into kindergarten, and during 4th and 6th grade.


Prenatal and ETS Exposure: Effects on Child Regulation
PI Rina Eiden
Co-I  Kenneth Leonard
          Gerard Connors (RIA)        
           Craig Colder (Psychology)
          Pamela Schuetze, Buffalo State College
Sponsor   National Institute of Drug Abuse
Current Funding  $2,891,000
Time   First year
This longitudinal, multi-method study  is investigating the impact of prenatal exposure to cigarettes on the development of self-regulation in infants over the first two years of life. Because most women who smoke cigarettes during pregnancy continue to smoke after delivery and have partners who smoke, children's exposure to environmental tobacco smoke (ETS) will also be examined


Rapid Pediatric Psychiatric Consultation -Quality Assurance Protocol-
P.I. Dr. Dubovsky
Co-Investigators: Drs. Jennifer Haak, David Kaye, Bruce Miller, Beth Smith, James Waxmonsky.
Externally Sponsored Research: Tower Foundation ($100, 000.00) & Blue Cross of WNY
The shortage of child psychiatrists is particularly acute in Western New York. A consultant may be able to help to meet the needs of the large number of psychiatric problems being treated in primary practices. The overall goal of this early intervention project is to demonstrate the clinical benefits and cost efficacy of a consultation service (comprehensive psychiatric evaluation) for high-risk children and adolescents with psychiatric disorders and treated in pediatrics and family medicine setting. 


Effects of Strattera and Behavior Therapy on the School and Home Functioning
of Elementary School Children with Attention-Deficit/Hyperactivity Disorder
(ADHD)
Investigator Initiated Study that compares the effects of multimodal
treatment with atomoxetine and behavioral modification therapy vs.
monotherapy with atomoxetine on the behavioral and academic functioning of
children with ADHD.MH069434 (Hawk)
2006-2010 (Co-Investigator)
Eli Lilly (Waschbusch/Waxmonsky)  2006-2007 (Co-PI)


Inhibitory control and clinical response in ADHD
Seeks to expand studies of inhibitory control in ADHD children,
investigating separate and combined effects of motivational incentives and
medication relative to normal control performance.  Goals include relating
results of the cognitive tasks to measures of behavior and classroom
performance taken in a naturalistic setting to bridge the gap between
laboratory studies and behavioral studies.


MH069614 (Pelham)     2005-2010
(Co-Investigator)
Behavior Modification in Young Children with ADHD
Seeks to study the effectiveness of no, low-intensity, or high-intensity
school-based behavioral treatments for young children with ADHD.  Specific
questions include whether we can prevent the need for medication in those
children and whether lower doses can be used when medication is necessary.
Treatment continues for three years with an additional follow-up assessment.


IES R423b06045 (Pelham)                  2006-2011 (Co-Investigator)   
Adaptive Treatments for Children with ADHD
Seeks to study the effects of high and low intensity behavior modification
techniques on the need for medication, social and academic outcomes in early
school age children with ADHD.

(NS039087) (Sallee)   2001-2006 (Co-Investigator)

Pre-School Supplement to Clonidine in ADHD
Funds the collection of data regarding the safety and efficacy of clonidine
and combined treatments of ADHD in children ages 5-7.

(MH064154) (Wood)    2002-2008 (Co-Investigator)
Depression and Child Asthma: Effects of Family Relations.
Seeks to study the relationship between asthma severity, depression and
family emotional climate.

Four Week, Double-Blind, Placebo-Controlled Phase III Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of Flexible Doses of Oral Ziprasidone in Children and Adolescent Subjects with Bipolar I Disorder (Manic or Mixed)  (A1281132)
Principal Investigator: David Kaye, MD
Sponsor: Pfizer

26-Week Open-Label Extension Study Evaluating the Safety and  Tolerability of Flexible Doses of Oral Ziprasidone in Children and Adolescents with Bipolar I Disorder (Manic or Mixed) (A1281133)
Principal Investigator: David Kaye, MD
Sponsor: Pfizer

Six Week, Double-Blind, Placebo-Controlled Phase III Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of Flexible Doses of Oral Ziprasidone in Adolescent Subjects with Schizophrenia (A1281134)
Principal Investigator: David Kaye, MD
Sponsor: Pfizer

26-Week Open-label extension study evaluation the safety and tolerability of flexible doses of oral ziprasidone in adolescent subjects with schizophrenia (A1281135)
Principal Investigator: David Kaye, MD
Sponsor: Pfizer