About the Program
The Department of Physiology and Biophysics at University at Buffalo, SUNY, School of Medicine and Biomedical Sciences has as its goal the study of normal and abnormal protein function within membranes and cells, normal and abnormal function of cells, organs and intact animals and humans using state-of-the-art biophysical, computational, genomic, proteomic and physiological techniques. We have particular strengths in the areas of ion channels, skeletal muscle physiology, epithelial cell biology, neurophysiology, vision, and environmental and cardiorespiratory physiology. Within the department we have faculty that actively participate in three interdisciplinary centers:
Areas of current research emphasis of our faculty include:
- Center for Research in Cardiovascular Medicine
- Center for Neuroscience
- Center for Single Molecule Biophysics
- elucidation of the mechanisms of ligand- and voltage-dependent channel gating
- stretch-activated channel function
- cell signaling and electrophysiological properties of cells within the CNS, heart and epithelial tissues
- adaptive responses of the body, including skeletal muscle, to environmental stress
- retinal function and development of visual systems
- neurodegenerative disorders (e.g., Juvenile Parkinson's disease and Huntington's disease)
- protein-protein interactions, protein folding and design
- calcium signaling within heart cells
- vascular biology
The diversity of faculty expertise and the collegial atmosphere have helped faculty within the department to secure independent federal funding. In recent years, grant funding of our Department has ranked as high as second in the country among comparable departments by the Association of Chairs of Departments of Physiology. Our laboratories have state-of-the-art equipment and computational facilities for implementing biophysical, genomic, proteomic and physiological studies within the department, which in part has been supported by funds provided by the Howard Hughes Medical Institute and Keck Foundation.
The Physiology and Biophysics Department at UB offers extensive educational programs in Physiology and Biophysics at the undergraduate, graduate, and postdoctoral levels. The innovative Undergraduate Program permits honors students and students majoring in Biology to complete an area of specialization within the Department and offers several courses in Physiology and Biophysics open to all undergraduates.
The Graduate Program, known for the excellence of the research faculty and flexibility of the program, offers training towards a Master's Degree or a Ph.D. degree in Biophysics, Physiology with a specialization in Biophysics, and interdisciplinary training leading to a Master's degree or a Ph.D. Degree in Neuroscience. Postdoctoral and medical student research opportunities are available in many laboratories.