The overall goal of the group is to study mechanisms of hypoxic-induced insults to the central nervous system. In addition to ongoing clinical sleep studies, we have developed an animal model of spontaneous intracranial hemorrhage which occurs after sustained hypoxia. This animal model has great relevance to intracranial hemorrhage or stroke which occurs as a complication of many neurological disorders. Our group is studying this model at the molecular, cellular, physiological, neuropathological and neurocognitive levels. Along with our research activities, the Group has a major interest in providing education to the University community regarding basic mechanisms of sleep, sleep disorders, sleep health and the effects of hypoxia on the nervous system.