University at Buffalo Orthopaedic Research Laboratory


Mark T. Ehrensberger, Ph.D.
Present Position
Director of Orthopaedic Research
Office Address
Orthopaedic Research Laboratory
162 Farber Hall
3435 Main Street
Buffalo, New York 14214-3000

(716) 829-2983 telephone
(716) 829-3945 fax
Education
Ph.D. Bioengineering, Syracuse University, May 2008
Concentrations: Bioelectrochemistry, Biomaterials
Dissertation: The In-Vitro Biological and Electrochemical Interactions of Electrically Polarized Commercially Pure Titanium Used for Orthopedic and Dental Applications

M.S. Bioengineering, Syracuse University, May 2002
Concentration: Biomechanics
Project: Motion Analysis of Unicompartment Knee Replacements

B.S. Bioengineering, Syracuse University, May 2000
Concentration: Bioinstrumentation
Honors Thesis: The Suppression of Distortion Product Oto-Acoustic Emissions in Rats

Research Interests
Dr. Ehrensberger is developing a new Orthopaedic Bioengineering research track within the Orthopaedic Research Laboratory at UB that will focus on understanding the biological and electrochemical interactions present at the surface of metallic biomaterials used in orthopaedic surgery. This research is an extension of Dr. Ehrensberger’s training in bioinstrumentation, biomaterials, and bioelectrochemistry.

In addition, Dr. Ehrensberger has a strong interest in applying engineering principles to understand the biomechanical mechanisms that dictate the performance of hard and soft tissue repairs commonly utilized in orthopaedics.

Publications
“Determination of Electrochemical Impedance with Potential Step Impedance Analysis.” Mark T. Ehrensberger and Jeremy L. Gilbert. (in process)

“Scanning Potential Step Impedance Analysis of Commercially Pure Titanium in Simulated Biological Conditions.” Mark T. Ehrensberger and Jeremy L. Gilbert. (in process)

“The Effect of Applied Potential on the 24 Hour Impedance Behavior of Commercially Pure Titanium in Simulated Biological Conditions.” Mark T. Ehrensberger and Jeremy L. Gilbert. (in process)

“The Relationship between Electrochemical Impedance and MC3T3 Pre-Osteoblast Behavior on Electrically Polarized Commercially Pure Titanium.” Mark T. Ehrensberger and Jeremy L. Gilbert. (in process)

“Influence of Suture Material on the Biomechanical Behavior of Suture-Tendon Specimens: A Controlled Study in Bovine Rotator Cuff.” Leslie J. Bisson, Leslie M. Manohar, Ryan D. Wilkins, Jennifer Gurske-Deperio, and Mark T. Ehrensberger. Am. J. Sports Med. 2008; 36: 907-912.

“The In-Vitro Response of Pre-Osteoblast Cells Cultured on Electrically Polarized Titanium: Implications for Fretting Corrosion of Modular Joint Replacments.”, Mark T. Ehrensberger. Gordon Research Conference-Bioelectrochemistry 2008.

“Is It Safe to Perform Aggressive Rehabilitation After Distal Biceps Tendon Repair Using the Modified 2-Incision Approach? A Biomechanical Study.” Leslie J. Bisson,, Jennifer Gurske de Perio, Alexander E. Weber, Mark T. Ehrensberger, and Cathy Buyea. Am J Sports Med. 2007 35: 2045-2050

“The Biological Significance of Electrically Polarized cpTi Joint Replacements.” M.T. Ehrensberger, AGEP Academic Excellence Symposium 2007.

“Potential Step Impedance Analysis of Titanium in PBS and Biological Media as a Function of Voltage and Time.” M. T. Ehrensberger and J. L. Gilbert, Proceedings of the 211th Electrochemical Society Meeting.

“Osteoblast Behavior and Electrochemical Impedance at Electrically Polarized Titanium Surfaces.” M. T. Ehrensberger and J. L. Gilbert, Proceedings of the 2007 Society for Biomaterials National Meeting.

“Electrochemical Control of Biological Interactions at the Metallic Biomaterial Interface: Fibrinogen Adsorption and Cell-Surface Interactions.” Jeremy L. Gilbert, Rob T.T. Gettens, Mark Ehrensberger, Proceedings of the 3rd International Symposium on Intelligent Artifacts and BIO-systems 2006.