Learning Issues:
1. The diagnosis of lipoma is usually made clinically. However, if the tumor mass begins to grow, be suspicious of a more aggressive lesion.
2. Routine radiographs or MRI may confirm that the soft tissue lesion is made of fat, and may be useful.
3. The differential diagnosis is important, since liposarcoma is one of the most common soft tissue sarcomas. Also consider the possibility of atypical lipoma, which tends to recur, or liposarcoma, which may metastasize. A thorough search of the entire resected specimen for possible areas of dedifferentiated liposarcoma should be done.
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