Images of Musculoskeletal Oncology

Extraskeletal Osteosarcoma

An 87 year old man had a painful, tender and growing mass in the medial aspect of one thigh for several months.
Note the mass on clinical photo taken just before surgery.
Routine x-rays including CT and MRI reveal a large irregular bony mass in the thigh compatible with the diagnosis of extraskeletal osteosarcoma. The differential diagnosis would include myositis ossification. Note the density of the tumor mass is about the same as that of the underlying femur, indicating the mass is bony rather than cartilaginous.





Histological examination of core needle biopsy demonstrates a high grade osteosarcoma.

Demonstrates the gross appearance of the widely resected lesion.
Demonstrates the appearance of the gross specimen sliced open, a rim of normal muscle is seen indicating a wide resection was performed. Several cavities are seen as a result of necrosis due to rapid growth of the lesions.
Chemotherapy was declined by the patient because of his advanced age. He did well immediately post operatively, however he succumbed to widespread metastases at about two years. There was no local recurrence.
Learning Issues:

Extraskeletal osteocarcoma is an entity to consider when a soft tissue mass is evaluated. Routine radiographs of extraskeletal osteogenic sarcoma will usually differentiate this entity from myositis ossification.


Images of Musculoskeletal Oncology
University at Buffalo Department of Orthopaedics