 | This routine radiograph and CT scan demonstrate an osteolytic lesion filling the proximal humerus, which has expanded the medullary space. Destruction of cortex is seen medially. The differential diagnosis would include a primary bone tumor such as chondrosarcoma, myeloma or a metastatic carcinoma. |
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 | This high power photomicrograph of the core
needle biopsy demonstrates a cellular cartilagionous neoplasm with a
number of mitotic figures which appear to be malignant cartilage.
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 | This core needle biopsy was interpreted as demonstrating a low-grade chondrosarcoma. The radiograph is most convincing for chondrosarcoma. Although the diagnosis of chondrosarcoma is often difficult, the combination of this radiograph together with evidence of its cartilaginous nature makes the diagnosis of chondrosarcoma - primary. A wide resection and allograft prosthetic reconstruction was then performed. |
 | Demonstrates a segment of normal humerus below the tumor, indicting a wide margin was obtained in this area. Histosection demonstrates articular cartilage resisting the advance of tumor into the joint. |
 | The large histosection of the resected specimen demonstrates the large cartilaginous neoplasm with cortical thinning and penetration, which reflects its malignant nature. Note the extension of the tumor into the shoulder cuff, and the clear evidence of a wide resection. |
 | AP radiograph demonstrates the combined allograft and prosthesis reconstructed two years post op. The allograft is solidly united to the patient's own humerus. |
| The patient remains free of disease ten years post op, but with little shoulder elevation. He was satisfied with his function and had been recurrence and metastases free. He died ten years later of unrelated causes, and was without evidence of the chondrosarcoma. |