UB SMBSUB Ophthalmology Department

Ophthalmic Pathology Service

Federico Gonzalez-Fernandez, MD, PhD

The goal of the service is to enhance communication between the ophthalmic surgeon and the pathology laboratories. We provide detailed histopathological information that can be correlated with patient history and other clinical data. In this way, histopathological studies have the greatest benefit to ongoing patient care.


To Submit Specimen Contact Directly To:


Dr. Gonzalez-Fernandez

E-mail: fg23@buffalo.edu
Office: 716-859-1581
Cell: 716-863-2291
Laboratory: 716-859-1987
Fax: 859-3221

Shipping Address:

Attention: Dr Gonzalez-Fernandez
Ophthalmic Pathology Service
Department of Pathology
Buffalo General hospital
100 High Street
Buffalo, New York 14203
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Dr. Gonzalez-Fernandez’s clinical service is primarily in anatomical pathology as it relates to Ophthalmology. He provides this resource to Western New York as the Ira Gile Ross & Elizabeth Pierce Olmsted Ross Chair in Ophthalmic Pathology.

Dr Gonzalez-Fernandez has established a unique collaboration between the Ross Eye Institute, and SUNY at Buffalo Departments of Ophthalmology and Pathology. This collaboration is orchestrated through Kaleida Health to provide the new service in Ophthalmic Pathology. The goal of the service is to provide a center of excellence for histopathological diagnosis of ocular disease.
This service is provided to ophthalmologists, and other surgical subspecialties that deal with the eye, ocular adnexa and orbit.

Specimens accepted for histopathological study include:

• Whole eyes
• Eye-lid lesions and resections
• Conjunctival lesions
• Cornea excisions and biopsies
• Orbital tumors including lacrimal gland
• Extraocular muscle resections and biopsies
• Vitreous biopsies and aspirates
• Temporal artery biopsies
• Ocular autopsy specimens

The service, which is coordinated by Dr. Gonzalez-Fernandez, provides a mechanism to mobilize the cross-departmental resources of the Kaleida and UB to provide a detailed study of tissues removed from the eye and ocular adnexa. Barriers between scientific specialties are absolved and ocular specimens receive are variety of available testing including:

• Detailed gross examination with macrophotography
• Detailed histopathological evaluation
• High resolution digital images of gross and microscopic findings
• Specialized histochemical stains
• Immunohistochemical studies
• Flow cytometric analysis
• Cytogenetics including fluorescence in situ hybridization
• Transmission and scanning electron microscopy
• Immunofluorescence
• Muscle pathology and enzyme histochemistry
• Genetic studies
• Detailed reports emphasizing clinical relevance of pathological findings


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