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Microbiology

University at Buffalo, State University of New York

Department of Microbiology and Immunology

Education
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GRADUATE COURSES

501  Graduate Microbiology (6 credits) LEC
Covers three major areas of microbiology: bacteriology, virology, and parasitology.  The bacteriology component includes bacterial physiology and structure, bacterial metabolism, bacterial genetics and disease processes.  The virology section of the course includes principles involved in the nature and biological activities of viruses, as well as virus-host interactions. This includes an in-depth consideration of the life cycle of selected viruses with representatives of the RNA and the DNA viruses.  The parasitology section of the course emphasizes unique features of parasite gene expression, metabolism, and adherence and invasion properties.  Representatives of both unicellular and multicellular parasites are considered. 

511 Bacterial Genetics (1 credit) LEC
Basic concepts of prokaryotic genetics, including DNA replication, transcription, translation, modes of genetic exchange, cell division, mutagenesis, and gene regulation. Sessions will include didactic lectures and in-class discussions of pertinent research papers. Use of classical and recombinant genetics in experimental design will be discussed.

512 Fundamentals of Immunology (4 credits) LEC
Anatomy and function of the immune system, cell interactions, antibody formation, antigen-antibody reactions, cell-mediated immunity, biological effects of immunological reactions.

516 Microbiology Laboratory Rotation (2 credits) LAB
Laboratory experiences in general and medical microbiology, virology, parasitology and immunology. Introduction to methods and experimental design in the research laboratory. Limited to incoming graduate students.

599 Supervised Teaching (1-3 credits) TUT
Experience in preparation and presentation of microbiology to undergraduate and professional students. Limited to graduate students in the Department.

607 DNA Replication and Repair (2 credits) SEM
DNA replication, repair and recombination.  Some readings assigned in advanced textbooks; however, most readings and presentations will be from current literature.

608 Regulation of Eukaryotic Gene Expression (2 credits) SEM
Organization of eukaryotic genes and the mechanisms of their regulation will be discussed.  Topics will be selected from current literature.  An attempt will be made to integrate the results of genetic, biochemical and physiological approaches employed to investigate each topic.  When appropriate, the impact of genomics and proteonomics will be emphasized.

609 Advanced Topics in Immunology (2 credits) SEM
Classes are organized around recent, ground-breaking research papers including, but not limited to, vaccine development, transplantation, autoimmunity, neuroimmunology and immunopharmacology.

611 Cytokines and Inflammation (2 credits) SEM
Current scientific literature in the fields of cytokines and inflammation, with an emphasis on molecular aspects of signal transduction.  Modern experimental models and techniques will be used.  Students will also learn to perform critical analyses of scientific literature and to plan future strategies for experimentation based on published findings.  Students will present lectures and write critical reviews of manuscript reprints.

613 Advanced Topics in Virology (2 credits) SEM
Advanced discussions on topics in virology. Classes are organized around recent papers in the virological literature. Topics include HIV, hantavirus infection, prions, and the hepatitis viruses.

614 Advanced Dental Microbiology (1 credit) LEC
Current concepts of microbiological aspects of caries and pulpal infections, response of host to pulpal infection, and control of bacteria and bacterial infections.

617-618 Special Instruction in Microbiology (1-2 credits) TUT
Introduction to special laboratory methods employed in molecular biology, clinical bacteriology, virology, immunology, immunochemistry, tissue culture, and cytogenetics.

619-620 Microbiology Seminar (1 credit) SEM
Advanced discussions on topics in bacteriology, virology, parasitology, and immunology. Students present papers on scientific material and participate in discussions.

624 Advanced Topics in Bacterial Pathogenesis (2 credits) SEM
Presentation, review and discussion of current scientific articles relating to bacterial pathogenesis.  New methodologies and state-of-the-art techniques will be introduced.

627 Advanced Topics in Molecular Parasitology (2 credits) SEM
Advanced discussions on topics in molecular parasitology. Classes are organized around current research in the literature.

636-675 Laboratory Research (1-12 credits) TUT

700 Thesis Guidance (1-4 credits) TUT
Preparation of the thesis based upon original graduate research. Discussions on presentation of data, its critical evaluation, and the candidate's review of pertinent literature in the field.

UNDERGRADUATE COURSES

301 Fundamentals of Microbiology (4 credits) LEC/LAB
Prerequisites:  college course in biology and chemistry; at least sophomore standing.
Principles of microbiology for students of medical technology, pharmacy, and nursing degree programs; introduces the structure and biological functions of microorganisms including bacteria, fungi, viruses and parasites.  Emphasizes the mechanisms by which microorganisms cause diseases in humans.  Also includes an immunology unit that introduces the principles and uses of immunology in infectious disease diagnosis and treatment.  The laboratory provides hands-on experience in techniques involved in isolation and characterization of microorganisms.  Three hours of lecture and one three-hour laboratory weekly.  Laboratory is required. 

319-320 Introduction to Scientific Literature (1credit) SEM
Prerequisites:  MIC301, BCH403 or BIO205, BIO319, permission of instructor.
Advanced discussions on topics in bacteriology, mycology, virology, parasitology, and immunology. Students present papers on current scientific material and participate in discussions.  

401 General Microbiology (6 credits) LEC
Prerequisites:  MIC301, BCH403 or BIO205, BIO319, permission of instructor.
Discusses in-depth the biology, physiology, genetics, and pathogenicity of selected bacteria, viruses, and parasites.  Lectures and current literature on molecular mechanisms. 

412 Fundamentals of Immunology  (4 credits) LEC
Prerequisites:  BIO210, BCH403 or BIO205, and permission of the instructor.
Anatomy and function of the immune system, cell interactions, antibody function, antigen-antibody reactions, cell-mediated immunity, biological effects of immunological reactions.  The content and organization of this course are similar to BIO468.

499 Independent Study  (1-8 credits) TUT
Prerequisite: permission of instructor
By arrangement with one or more faculty members; participation in research project involving limited research laboratory experience in some aspect of microbiology or immunology. 

 


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