Department of Biochemistry
School of Medicine & Biomedical Sciences
Lab Facilities

Department faculty members currently direct 20 extramurally-funded research projects, accounting for annual expenditures of approximately $3.2 million, in addition to participating in a variety of collaborative efforts with investigators from around the world. Their labs are well-equipped for analysis of macromolecular structure and function, as well as for molecular and cellular biological studies in prokaryotic and eukaryotic organisms. Active research programs exist in the areas of protein structure and function, membrane structure and transport, regulation of gene expression, DNA repair, metabolic regulation and cellular development and differentiation. These are supported by multi-user facilities for online analysis of protein and nucleic acid databases including software for access and manipulation, high resolution NMR and crystallography; a cell imaging core that includes confocal and electron microscopy; a nucleotide sequencing and oligonucleotide synthesis facility; a microarray facility for analysis of regulation of gene expression during development, in response to environmental stresses, or under pathogenic stress; a mouse knockout/transgenesis core for construction of animal models of human disease; and a mass spectrometry facility for proteome analysis. Department laboratories are located both in the new Biomedical Research Building and in newly renovated space in the adjoining Farber Hall. Both buildings include shared instrumentation modules for standard biochemical and molecular biological analysis.

Link to Core Research Facilities