SPRING SEMESTER 2009
M/W/F 8:30 am in Farber 136

Course Coordinator:  Dr. Piero Bianco (pbianco@buffalo.edu)
MIC/BIO/BCH 522 Spring 2009 Class Schedule [PDF]

This course is cross-listed in the Departments of Microbiology, Biochemistry and Biology. Recognizing that a detailed, quantitative understanding of the interactions between proteins and nucleic acids is key to studying and understanding all aspects of nucleic acid metabolism, this course will make students intimately familiar with all relevant aspects of proteins and how they interact with nucleic acids as well as the state of the art approaches to performing quantitative studies. It will be taught by a team of faculty with expertise in these areas.

Section 1: Structures of nucleic acids

Section 2: Protein structure and motifs as they pertain to interactions with nucleic acids.

Section 3: Protein Nucleic Acid systems, e.g. DNA replication, repair, recombination, transcription, translation, etc.

Section 4: Methods of purification of nucleic acid-binding proteins.

Section 5: Methods to study and analyze protein-nucleic acid interactions.