Postdoctoral Position in Ion Channel Physiology & Biophysics

State University of New York at Buffalo
Buffalo, New York, U.S.A.

A postdoctoral position is available in the Physiology/Biophysics Department at the State University of New York at Buffalo, New York. One of our research projects involves studies of structure and function mechanisms of ion channels, in particular, the VR1 receptor, a recently cloned sensory ion channel for detection of heat, acids, and capsaicin - the hot ingredient of spicy food and peppers. We are primarily interested in the mechanistic aspects of heat activation and multimodal functions of the receptor, i.e. how individual stimuli activate the channel and how they interact with each other. Our approach involves single-channel patch-clamp recording and site-directed mutagenesis. The selected candidate will join us to expand our on-going research on this project. The candidate will be responsible for carrying out patch-clamp experiments, analyzing data and writing papers.

Besides the VR1 project, our research program also involves other projects including development of advanced single-channel data analysis techniques and development of computational algorithms for protein bioinformatics and structure imaging. The candidate will have an excellent opportunity to get exposed to a variety of interesting research areas and interact with both theoreticians and experimentalists with different expertise.

The funding for this position is secure for at least four coming years assuming good progress. The applicants must be self-motivated, career-oriented, and have a strong background in the field of ion channels. Experience in patch-clamp recording is required. Good knowledge on quantitative data analysis and protein biophysics is particularly appreciated. Familiarity with oocyte handling, RNA injection, and mammalian cell-line transfection is preferred.

Interested applicants should submit a curriculum vitae, list of publications and a statement of research interests to:

Dr. Feng Qin (qin@acsu.buffalo.edu)
Department of Physiology and Biophysics
State University of New York at Buffalo
Buffalo, NY 14214
U.S.A.

Email submission to qin@acsu.buffalo.edu is encouraged.

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