BPH505 - Biophysical Basics: Processes

Credit: 3
Registration no: 417230
Other information: http://studentresponse.buffalo.edu/schedule/
Coordinator: Dr. S Ohki
See Dr. Ohki for details of the course.

BPH510 - Introductory Quantitative Biology

Credits: 3
Registration no: 285207
Other information: http://studentresponse.buffalo.edu/schedule/
Coordinator: Dr. F Qin, 318H Cary Hall, qin@acsu.buffalo.edu

This course focuses on data analysis, mathematical modeling and computational analysis of problems in cellular and molecular biology. Topics are selected from a variety of areas and cover most commonly used analysis and modeling approaches. These include, for example, chemical kinetics, diffusion, electrotonic interactions, single molecule kinetics, DNA/protein sequence analysis, macromolecular simulation, etc. In addition to basic theory, students will also gain hands-on experience on the use of computers and various computer programs. Abundant opportunity will be provided for students who have specific interests.

The course will be team-taught (R. Rasmusson, A. Keleshian, F. Sachs, M. Slaughter, Y. Zhou, F. Qin) and is appropriate for graduate students and advanced undergraduates. Final evaluation of the course will be based on projects.

Prerequisites:
A minimum background of introductory calculus, physics and biology is required.

Time and Place:
Twice per week for 3 hours. Day of the week and time to be decided among enrolled students and instructors.

Contact Information:
Dr. F Qin
Department of Physiology and Biophysics
318H Cary Hall
Email: qin@acsu.buffalo.edu

Course Outline: (Approximately 2 weeks per topic)

• Chemical kinetics
  Dr. Claudio Grosman (grosman@buffalo.edu)
• Diffusion
  Dr. Fred Sachs (sachs@buffalo.edu)
• Cable theory
  Dr. Malcom Slaught (mslaught@buffalo.edu)
• Sequence analysis
  Dr. Philip A Gottlieb (philgott@acsu.buffalo.edu)
• Single molecule kinetics
  Dr. Feng Qin (qin@acsu.buffalo.edu)
• Macromolecular simulation
  Dr. Kenneth Snyder (ksnyder@acsu.buffalo.edu)

Homework:
There will be homework assignments for each topic. The number of assignments will depend on the individual lecturers.

Project:
There will be one final project. You are allowed to select the topic you are most interested, as long as the project matches one of the topics covered in the course. You should consult the corresponding lecturer about the quality of your project before you start.

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